cord1 PRA in MLHDs: KC Advice Oct. 2009

Following a meeting between Breed Council representatives and Prof. Jeff Sampson, the KC’s geneticist, he agreed to write to any breeder of Miniature Long-haired Dachshunds who is still producing and registering cord1 Affected puppies.

He will also be writing to all MLHD breeders (including those who are not Breed Club members) to advise them of the latest good practice in relation to the cord1 mutation.

The advice is as follows:

  • If a dog tests normal, then there are obviously no breeding restrictions on the dog because it can only pass normal versions of the gene to its offspring.
  • If a dog tests as a carrier, and it is to be bred from, then it should not mated to another untested dog, a DNA tested carrier or a DNA tested affected dog. The reason for this is that the risk of producing further affected dogs from such matings is unacceptably high. However, a tested carrier can be mated to another DNA tested normal dog. The progeny of such a mating will be either a normal dog or a carrier dog. Importantly, none of the offspring of a carrier/normal mating will become clinically affected. Ideally, all of the progeny of such a mating should also be DNA tested to determine whether they are normal or carriers. It is imperative that such progeny are DNA tested before they are mated in the future.
  • If a dog is tested as an affected, then such dogs should not be bred from unless there are compelling reasons to do so. If an affected dog is to be mated, then it must be mated to another DNA tested normal dog. All of these progeny will be clinically normal carriers. Obviously, if any of these are to be bred from in the future, then they should only be bred to a DNA tested dog, as above.

This advice is only directed at MLHD breeders since the cord1 screening programme has now been in place for 5 years and there is no reason for breeders to be producing Affected puppies.

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